Research Achievements
| 2012 | 2011 | 2010 | 2009 | 2008 |
| Papers| Books| International Conferences |
Papers
Nagai‚ M.‚ Furihata‚ T.‚ Matsumoto‚ S.‚ Ishii‚ S.‚ Motohashi‚ S.‚ Yoshino‚ I.‚ Ugajin‚ M.‚ Miyajima‚ A.‚ Matsumoto‚ S.‚ Chiba‚ K. Identification of a new organic anion transporting polypeptide 1B3 mRNA isoform primarily expressed in human cancerous tissues and cells.
Biochem Biophys Res Commun. 2012; 418 (4): 818-823
Yamashita‚ J.‚ Iwamura‚ C.‚ Mitsumori‚ K.‚ Hosokawa‚ H.‚ Sasaki‚ T.‚ Takahashi‚ M.‚ Tanaka‚ H.‚ Kaneko‚ K.‚ Hanazawa‚ A.‚ Watanabe‚ Y.‚ Shinoda‚ K.‚ Tumes‚ D.‚ Motohashi‚ S.‚ Nakayama‚ T. Murine Schnurri-2 controls Natural Killer cell function and lymphoma development.
Leuk. Lymphoma 2012; 53 479-486
Takeuchi K‚ Umeki Y‚ Matsumoto N‚ Yamamoto K‚ Yoshida M‚ Suzuki K‚ Aratani Y. Severe neutrophil-mediated lung inflammation in myeloperoxidase-deficient mice exposed to zymosan.
Inflammation Res 2012; 6 (13): 197-205
Hayashi D‚ Tamura A‚ Tanaka H‚ Yamazaki Y‚ Watanabe S‚ Suzuki K‚ Suzuki K‚ Sentani K‚ Yasui W‚ Rakugi H‚ IsakaY‚ Tsukita S. Defiency of claudin-18 causes paracellular H+ leakage‚ up-regulation of interleukin-1 beta‚ and atrophic gastritis in mice.
Gastroenterology 2012; 142 (2): 292-304
Fujimori Y‚ Sato T‚ Hayata T‚ Nagao T‚ Nakayama M‚ Nakayama T‚ Sugamata R‚ Suzuki K. Novel anti-viral characters of nanosized copper(I) iodide particles showing inactivation activity against 2009 pandeminc H1N1 influenza virus.
Applied Environ Microbiol 2012; 78 (4): 951-955
Koshio O‚ Nagao T‚ Mabuchi A‚ Ono Y‚ Suzuki K. Apoptotic signaling in endothelial cells with neutrophil activation.
Mol Cell Biochem 2012; 363 (1-2): 269-280
Shitara‚ Y.‚ Takeuchi‚ K.‚ Nagamatsu‚ Y.‚ Wada‚ S.‚ Sugiyama‚ Y.‚ and Horie‚ T. Long-lasting inhibitory effects of cyclosporin A‚ but not tacrolimus‚ on OATP1B1- and OATP1B3-mediated uptake.
Drug Metab. Pharmacokinet. 2012; in press
Koshizaka M‚ Takemoto M‚ Sato S‚ Tokuyama H‚ Fujimoto M‚ Okabe E‚ Ishibashi R‚ Ishikawa T‚ Tsurutani Y‚ Onishi S‚ Mezawa M‚ He P‚ Honjo S‚ Ueda S‚ Saito Y‚ Yokote K An Angiotensin II Type 1 Receptor Blocker Prevents Renal Injury via Inhibition of the Notch Pathway in Ins2 Akita Diabetic Mice
Experimental Diabetes Research 2012; in press
Tanaka H‚ Ohwada C‚ Hashimoto S‚ Sakai S‚ Takeda Y‚ Abe D‚ Takagi T‚ Ohshima K‚ Nakaseko C. Leukemic presentation of ALK-negative anaplastic large cell lymphoma in a patient with myelodysplastic syndrome.
Intern Med 2012; 51 (2): 199-203
Shimizu N‚ Nakaseko C‚ Sakaida E‚ Ohwada C‚ Takeuchi M‚ Tanaka S‚ Muto T‚ Kawaguchi T‚ Tsukamoto S‚ Sakai S‚ Takeda Y‚ Abe D‚ Yokote K‚ Iseki T‚ Kanai K‚ Misawa S‚ Kuwabara S. Factors associated with the efficiency of peripheral blood stem cell harvest in patients with POEMS syndrome undergoing autologous peripheral blood stem cell transplantation.
Bone Marrow Transplant 2012; in press
Sazuka S‚ Takahashi Y‚ Sato T‚ Nakagawa T‚ Furuya Y‚ Saito M‚ Saito K‚ Kawaguchi T‚ Nakaseko C‚ Katsuno T‚ Yokosuka O. Endoscopic findings of small intestinal EBV-associated T-cell lymphoproliferative disorder.
Endoscopy 2012; in press
Sugamata R‚ Dobashi H‚ Nagao T‚ Yamamoto K‚ Nakajima N‚ Sato Y‚ Aratani Y‚ Oshima M‚ Sata T‚ Kobayashi K‚ Kawachi S‚ Nakayama T‚ Suzuki K. The contribution of neutrophil-derived myeloperoxidase in the early phase of fulminant acute respiratory distress syndrome induced by influenza virus infection.
Microbiol Immunol. 2012; 56 (3): 171-182
Uekusa Y‚ Inamine A‚ Yonekura S‚ Horiguchi S‚Fujimura T‚Sakurai D‚ Yamamoto‚Hanazawa T‚Okamoto Y. Immunological parameters with the development of allergics rhinitis:A preliminary prospective study.
Am J Rhinol Alleg. 2012; 26 (2): 92-96
Aoysgi Y‚Kuroda M‚Asada S‚Tanaka S‚Tanio M‚Aso M‚Okamoto Y‚Nakayama T‚Saito Y‚Bujo H. Fibrin glue is a candidate scaffold for long-term therapeutic protein expression in spontaneously differentiated adipocytes vitro.
Experimental Cell Reseach 2012; 318 (1): 1090-2422
Inoue H‚ Mashimo Y‚ Funamizu M‚ Yonekura S‚ Shigtoshi H‚ Shimojo N‚ Kohno Y‚ Okamoto Y‚ Hata A‚ Suzuki Y. Association of the MMP9 gene with childhood cedar pollen sensitization and pollinosis.
J Hum Genet on line publication 2012; 1-8
Katada K‚ Tomonaga T‚ Satoh M‚ Matsushita K‚ Tonoike Y‚ Kodera Y‚ Hanazawa T‚ Nomura F‚ Okamoto Y. Plectin promotes migration and invasion of cancer cells and is a novel prognostic marker for head and neck squamous cell carcinoma.
J Proteomics 2012; 75 (6): 1803-1815
Yonekura S‚ Okamoto Y‚ Horiguchi S‚ Sakurai D‚ Chazono H‚ Hanazawa T‚ Okawa T‚ Aoki S‚ Konno A. Effects of aging on the natural history of seasonal allergic rhinitis in middle-aged subjects in South chiba‚ Japan.
Int Arch Allergy Immunol. 2012; 157 (1): 73-80
Ayako Inamine‚Daijyu Sakurai‚ Shigetoshi Horiguchi‚ Syu-ji Yonekura‚ Toyoyuki Hanazawa‚ Hiroyuki Hosakawa‚ Asaka Matuura-Suzuki‚Toshinori Nakayama‚ Yoshitaka Okamoto‚ Sublingual administration of Lactobacillus paracasei KW3110 inhibits Th2-dependent allergic responses via upregulation of PD-L2 on dendritic cells.
Clin Immunol. 2012; 143 (2): 170-179
Kawakami K‚ Enokida H‚ Chiyomaru T‚ Tatarano S‚ Yoshino H‚ Kagara I‚ Gotanda T‚ Tachiwada T‚ Nishiyama K‚ Nohata N‚ Seki N‚ Nakagawa M. The functional significance of miR-1 and miR-133a in renal cell carcinoma.
Eur J Cancer. 2012; 48 (6): 827-836
Yoshino H‚ Enokida H‚ Kawakami K‚ Chiyomaru T‚ Tatarano S‚ Hidaka H‚ Yamasaki T‚ Gotanda T‚ Tachiwada T‚ Nohata N‚ Nishiyama K‚ Seki N‚ Nakagawa M. Tumor suppressive microRNA-1 mediated novel apoptosis pathways through direct inhibition of splicing factor arginine/serine-rich 9 (SRSF9/SRp30c) in bladder cancer.
Biochem Biophys Res Commun. 2012; 417 (1): 588-593
Tatarano S‚ Chiyomaru T‚ Kawakami K‚ Enokida H‚ Yoshino H‚ Hidaka H‚ Nohata N‚ Yamasaki T‚ Gotanda T‚ Tachiwada T‚ Seki N‚ Nakagawa M. Novel oncogenic function of mesoderm development candidate 1 (MESDC1) and its regulation by MiR-574-3p in baldder cancer cell lines.
Int J Oncol. 2012; 40 (4): 951-959
Kojima S‚ Chiyomaru T‚ Kawakami K‚ Yoshino H‚ Enokida H‚ Nohata N‚ Fuse M‚ Ichikawa T‚ Naya Y‚ Nakagawa M‚ Seki N. Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer.
Br J Cancer. 2012; 106 (2): 405-413
Moriya Y‚ Nohata N‚ Kinoshita T‚ Mutallip M‚ Okamoto T‚ Yoshida S‚Suzuki M‚ Yoshino I‚ Seki N. Tumor suppressive microRNA-133a regulates novel molecular networks in lung squamous cell carcinoma.
J Hum Genet. 2012; 57 (1): 38-45
Kinoshita T‚ Nohata N‚ Yoshino H‚ Hanazawa T‚ Kikkawa N‚ Fujimura L‚ Chiyomaru T‚ Kawakami K‚ Enokida H‚ Nakagawa M‚ Okamoto Y‚ Seki N. Tumor suppressive microRNA-375 regulates lactate dehydrogenase B in maxillary sinus squamous cell carcinoma.
Int J Oncol. 2012; 40 (1): 185-193
Okamoto N‚ Hayashi S‚ Masui A‚ Kosaki R‚ Oguri I‚ Hasegawa T‚ Imoto I‚ Makita Y‚ Hata A‚ Moriyama K‚ Inazawa J. Deletion at chromosome 10p11.23-p12.1 defines characteristic phenotypes with marked midface retrusion.
J Hum Genet. 2012; 57 (3): 191-196
Inoue H‚ Mashimo Y‚ Funamizu M‚ Yonekura S‚ Horiguchi S‚ Shimojo N‚ Kohno Y‚ Okamoto Y‚ Hata A‚ Suzuki Y. Association of the MMP9 gene with childhood cedar pollen sensitization and pollinosis.
J Hum Genet. 2012; 57 (3): 176-183
Narisawa A‚ Komatsuzaki S‚ Kikuchi A‚ Niihori T‚ Aoki Y‚ Fujiwara K‚ Tanemura M‚ Hata A‚ Suzuki Y‚ Relton CL‚ Grinham J‚ Leung KY‚ Partridge D‚ Robinson A‚ Stone V‚ Gustavsson P‚ Stanier P‚ Copp AJ‚ Greene ND‚ Tominaga T‚ Matsubara Y‚ Kure S. Mutations in genes encoding the glycine cleavage system predispose to neural tube defects in mice and humans.
Hum Mol Genet. 2012; 21 (7): 1496-1503
Onouchi Y‚ Suzuki Y‚ Suzuki H‚ Terai M‚ Yasukawa K‚ Hamada H‚ Suenaga T‚ Honda T‚ Honda A‚ Kobayashi H‚ Takeuchi T‚ Yoshikawa N‚ Sato J‚ Shibuta S‚ Miyawaki M‚ Oishi K‚ Yamaga H‚ Aoyagi N‚ Iwahashi S‚ Miyashita R‚ Murata Y‚ Ebata R‚ Higashi K‚ Ozaki K‚ Sasago K‚ Tanaka T‚ Hata A. ITPKC and CASP3 polymorphisms and risks for IVIG unresponsiveness and coronary artery lesion formation in Kawasaki disease.
Pharmacogenomics J. 2012; in press
Hayashi S‚ Okamoto N‚ Chinen Y‚ Takanashi J‚ Makita Y‚ Hata A‚ Imoto I‚ Inazawa J. Novel intragenic duplications and mutations of CASK in patients with mental retardation and microcephaly with pontine and cerebellar hypoplasia (MICPCH).
Hum Genet. 2012; 131 99-110
Yamatoji M‚ Kasamatsu A‚ Kouzu Y‚ Koike H‚ Sakamoto Y‚ Ogawara K‚ Shiiba M‚ Tanzawa H‚ Uzawa K. Dermatopontin: A potential predictor for metastasis of human oral cancer.
Int J Cancer. 2012; 130 (12): 2903-2911
Ishiwata J‚ Kasamatsu A‚ Sakuma K‚ Iyoda M‚ Yamatoji M‚ Usukura K‚ Ishige S‚ Shimizu T‚ Yamano Y‚ Ogawara K‚ Shiiba M‚ Tanzawa H‚ Uzawa K. State of heat shock factor 1 expression as a putative diagnostic marker for oral squamous cell carcinoma.
Int J Oncol. 2012; 40 (1): 47-52
Ono K‚ Shiiba M‚ Yoshizaki M‚ Ogawara K‚ Ishihara T‚ Yonemori Y‚ Oide T‚ Uzawa K‚ Nakatani Y‚ Tanzawa H. Immunoglobulin G4-Related Sclerosing Inflammatory Pseudotumors Presenting in the Oral Cavity.
J Oral Maxillofac Surg. 2012; in press
Uchibori K‚ Kasamatsu A‚ Sunaga M‚ Yokota S‚ Sakurada T‚ Kobayashi E‚ Yoshikawa M‚ Uzawa K‚ Ueda S‚ Tanzawa H‚ Sato N. Establishment and characterization of two 5-fluorouracil-resistant hepatocellular carcinoma cell lines.
Int J Oncol. 2012; 40 (4): 1005-1010
Uehara E‚ Shiiba M‚ Shinozuka K‚ Saito K‚ Kouzu Y‚ Koike H‚ Kasamatsu A‚ Sakamoto Y‚ Ogawara K‚ Uzawa K‚ Tanzawa H. Upregulated expression of ADAM12 is associated with progression of oral squamous cell carcinoma.
Int J Oncol. 2012; 40 (5): 1414-1422
Ota‚ R‚ Iwasawa‚ M.T. ‚ Ohkusu‚ K. ‚ Kambe‚ N. ‚ Matsue‚ H. Maximum growth temperature test for cutaneous Mycobacterium chelonae predicts the efficacy of thermal therapy.
Journal of Dermatology 2012; 39 (2): 205-206
Li‚ K.‚ Yao‚ J. ‚ Shi‚ L. ‚ Sawada‚ N.‚ Chi‚ Y.‚ Yan‚ Q.‚ Matsue‚ H.‚ Kitamura‚ M.‚ Takeda‚ M. Reciprocal regulation between proinflammatory cytokine-induced inducible NO synthase (iNOS) and connexin43 in bladder smooth muscle cells.
Journal of Biological Chemistry 2012; 286 (48): 41552-41562
Mizuno T‚ Sakai H‚ Nishikomori R‚ Oshima K‚ Ohara O‚ Hata I‚ Shigematsu Y‚ Ishige T‚ Tamura K‚ Arakawa H. Novel mutations of MVK gene in Japanese family members affected with hyperimmunoglobulinemia D and periodic fever syndrome.
Rheumatol Int. 2012; in press
Takagi S‚ Saito Y‚ Hijikata A‚ Tanaka S‚ Watanabe T‚ Hasegawa T‚ Mochizuki S‚ Kunisawa J‚ Kiyono H‚ Koseki H‚ Ohara O‚ Saito T‚ Taniguchi S‚ Shultz LD‚ Ishikawa F. Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation.
Blood. 2012; 119 (12): 2768-2777
Izawa K‚ Hijikata A‚ Tanaka N‚ Kawai T‚ Saito MK‚ Goldbach-Mansky R‚ Aksentijevich I‚ Yasumi T‚ Nakahata T‚ Heike T‚ Nishikomori R‚ Ohara O. Detection of Base Substitution-Type Somatic Mosaicism of the NLRP3 Gene with >99.9% Statistical Confidence by Massively Parallel Sequencing.
DNA Res. 2012; 19 (2): 143-152
Akutsu Y‚ Yasuda S‚ Nagata M‚ Izumi Y‚ Okazumi S‚ Shimada H‚ Nakatani Y‚ Tsujii H‚ Kamada T‚ Yamada S‚ Matsubara H‚ A phase l/ll clinical trial of preoperative short-course carbon-ion radiotherapy for patients with aquamous cell carcinoma of the esophagus.
J Surg Oncol 2012; 105 (8): 750-755
Nakagomi D‚ Ikeda K‚ Kawashima H‚ Kobayashi Y‚ Suto A‚ Nakajima H. Bucillamine-induced yellow nail in Japanese patients with rheumatoid arthritis: two case reports and a review of 33 reported cases.
Rheumatol Int 2012; in press
Saito Y‚ Kagami S-I‚ Kawashima S‚ Takahashi K‚ Ikeda K‚ Hirose K‚ Oshitari T‚ Yamamoto S‚ Okamoto Y‚ Nakajima H Roles of CRTH2+ CD4+ T cells in IgG4-related lacrimal gland enlargement.
Int. Arch. Allergy Immunol 2012; in press
Watarai H‚ Sekine-Kondo E‚ Shigeura T‚ Motomura Y‚ Yasuda T‚ Satoh R‚ Yoshida H‚ Kubo M Kawamoto H‚ Koseki H‚ Taniguchi M. Development and Function of Invariant Natural Killer T cells Producing TH2- and TH17-cytokines.
PLoS Biology 2012; 10 (2): e1001255-
Satoh‚ M.‚ Andoh‚ Y.‚ Clingan‚ S. C.‚ Ogura‚ H.‚ Fujii‚ S.‚ Nakayama‚ T.‚ Taniguchi‚ M.‚ Hirata‚ N.‚ Ishimori‚ N.‚ Tsutsui‚ H.‚ Onoe‚ K.‚ and Iwabuchi‚ K. Type II NKT cells stimulate diet-induced obesity by mediating adipose tissue inflammation‚ steatohepatitis and insulin resistance.
PLoS ONE 2012; 7 (2): e30568-
Kidoya‚ H.‚ Kunii‚ N.‚ Naito‚ H.‚ Muramatsu‚ T.‚ Okamoto‚ Y.‚ Nakayama‚ T.‚ and Takakura‚ N. The apelin/APJ system induces maturation of the tumor vasculature and improves the efficiency of immune therapy.
Oncogene 2012; in press
Aoyagi‚ Y.‚ Kuroda‚ M.‚ Asada‚ S.‚ Tanaka‚ S.‚ Konno‚ S‚. Tanio‚ M.‚ Aso‚ M.‚ Okamoto‚ Y.‚ Nakayama‚ T.‚ Saito‚ Y.‚ Bujo‚ H. Fibrin glue is a candidate scaffold for long-term therapeutic protein expression in spontaneously differentiated adipocytes in vitro.
Exp Cell Res. 2012; 318 (1): 8-15
Alexopoulos P‚ Guo LH‚ Tsolakidou A‚ Kratzer M‚ Grimmer T‚ Westerteicher C‚ Jiang M‚ Bujo H‚ Diehl-Schmid J‚ Kurz A‚ Perneczky R. Interrelations between CSF Soluble A¦ĀPP¦Ā‚ Amyloid-¦Ā 1-42‚ SORL1‚ and Tau Levels in Alzheimer”Ēs Disease.
J Alzheimers Dis. 2012; 28 (3): 543-552
Gotoda T‚ Shirai K‚ Ohta T‚ Kobayashi J‚ Yokoyama S‚ Oikawa S‚ Bujo H‚ Ishibashi S‚ Arai H‚ Yamashita S‚ Harada-Shiba M‚ Eto M‚ Hayashi T‚ Sone H‚ Suzuki H‚ Yamada N. Diagnosis and Management of Type I and Type V Hyperlipoproteinemia.
J Atheroscler Thromb. 2012; 19 (1): 1-12
Arai H‚ Ishibashi S‚ Bujo H‚ Hayashi T‚ Yokoyama S‚ Oikawa S‚ Kobayashi J‚ Shirai K‚ Ota T‚ Yamashita S‚ Gotoda T‚ Harada-Shiba M‚ Sone H‚ Eto M‚ Suzuki H‚ Yamada N. Management of Type IIb Dyslipidemia.
J Atheroscler Thromb. 2012; 19 (2): 105-114
Books
Nagai M‚ Furihata T‚ Matsumoto S‚ Ishii S‚ Motohashi S‚ Yoshino I‚ Ugajin M‚ Miyajima A‚ Matsumoto S‚ Chiba K. Identification of a new organic anion transporting polypeptide 1B3 mRNA isoform primarily expressed in human cancerous tissues and cells Biochemical and Biophysical Research Communications 2012; in press
Hori T‚ Jin L‚ Fujii A‚ Furihata T‚ Nagahara Y‚ Chiba K‚ Hosokawa M. Dexamethasone-mediated transcriptional regulation of rat carboxylesterase 2 gene. Xenobiotica. 2012; in press
Iikura M‚ Furihata T‚ Mizuguchi M‚ Nagai M‚ Ikeda M‚ Kato N‚ Tsubota A‚ Chiba K. ENT1‚ a ribavirin transporter‚ plays a pivotal role in antiviral efficacy of ribavirin in a hepatitis C virus replication cell system. Antimicrob Agents Chemother. 2012; in press
Tsubota A‚ Shimada N‚ Yoshizawa K‚ Furihata T‚ Agata R‚ Yumoto Y‚ Abe H‚ Ika M‚ Namiki Y‚ Chiba K‚ Fujise K‚ Tada N‚ Aizawa Y. Contribution of ribavirin transporter gene polymorphism to treatment response in peginterferon plus ribavirin therapy for HCV genotype 1b patients. Liver Int. 2012; in press
International Conferences
Shinoda K. CD69 regulates the formation of resting T helper memory
14th International Conference on Lymphocyte Activation and Immune Regulation 2012-3-3 NewPort Beach/USA
Endo Y. Eomesodermin controls IL-5 production in memory Th2 cells through the inhibition of GATA3 activity
14th International Conference on Lymphocyte Activation and Immune Regulation 2012-2-3 Newport Beach/USA
Kazuhiko Onishi‚ Hiroshi Imada‚ Shigeo Yasuda‚ Shigeru Yamada‚ Makoto Shinoto‚ Satoshi Endo‚ Tadashi Kamada‚ Osamu Yokosuka Efficacy and safety of short-course carbon ion radiotherapy for elderly hepatocellular carcinoma patients‚
The 22nd Congress of the Asian Pacific Association for the Study of the Liver 2012-2-16 Taipei/Taiwan
Tadashi Kamada Overview of the Carbon Ion Radiotherapy at HIMAC
2th NIRS-ETOILE Joint Symposium on Carbon Ion Therapy 2012-11-25 Lyon/France
Satoshi Kishida‚Tomomi Furihata‚Atsuko kamiichi‚Shinya Kawamatu‚ Kan Chiba Establishment and functional characterization of a novel conditionally immortalized human brain microvascular endothelial cell line
International Symposium on PPF of Molecular Pharmacokinetics 2012-1-30 Tokyo/Japan
Tomomi Furihata‚ Miki Nagai‚ Seiya Ishii‚ Sayaka Matsumoto”¢Shinichiro Motohashi‚ Ichiro Yoshino‚ Kan Chiba A novel variant is a bona fide organic anion transporting polypeptide 1B3 in cancer cells
International Symposium on PPF of Molecular Pharmacokinetics 2012-1-16 Tokyo/Japan
